婴幼儿轮状病毒肠炎122例临床分析

Clinical analysis of 122 cases with infant rotavirus enteritis

目的探讨婴幼儿轮状病毒(RV)肠炎的临床特点,提高对婴幼儿轮状病毒肠炎的临床认识和诊治水平。方法回顾性分析本科2009～2011年收治的122例婴幼儿轮状病毒肠炎患儿的临床资料。结果 122例RV肠炎患儿经治疗1～2d后体温下降,3～5d腹泻呕吐停止,平均住院6d;心肌酶谱异常者占25.4%(31/122),丙氨酸氨基转移酶增高者占8.2%(10/122),心肌酶及肝酶异常均为一般性,可随病情好转而渐恢复正常。结论轮状病毒仍是秋冬季婴幼儿急性腹泻的主要病原之一,目前尚无特效治疗,应用调节肠道菌群和对症处理、防治轮状病毒感染引起的多脏器损害可取得满意疗效。

Objective To explore the clinical characteristic of infant rotavirus enteritis, and to improve the clinical cognition and diagnosis level of infant rotavirus enteritis. Methods Analyzed the clinical data of 122 cases of infants with rotavirus enteritis in pediatrics retrospectively from 2009 to 2011. Results In 122 cases of infants with RV enteritis,the temperature dropped after being treated for 1-2 days, diarrhea and vomiting stopped after 3-5 days＇ treatment, and the average hospital stay was 6 days;myocardial zymogram of abnormalities accounted for 25.4%（31/122）, and the patients whose ala - nine aminotransferase level increased accounted for 8.2% （10/122）, myocardial enzymes and liver enzyme abnormalities are common, with the condition improved and gradually returned to normal. Conclusion Rotavirus acute infantile diarrhea in autumn and winter is still one of the main pathogens, for there is no especially effective treatment at present. We can obtain satisfactory curative effect from regulating intestinal microflora, symptomatic treatment and prevention and treatment of RV infections caused by multiple organ damage.