川南地区原发性高血压中医证型与血脂的相关性分析

Analysis of the Correlation between Essential Hypertension and Lipid in TCM Syndrome in Southern Sichuan Area

目的:研究血脂与川南地区原发性高血压的关系。方法:检测四川泸州及附近地区140例原发性高血压患者和40例血压正常者血压、血脂并进行比较。结果:高血压4种证型在上述指标中,肝火亢盛证、阴虚阳亢证及痰湿壅盛证与正常组TG比较差异有统计学意义(P<0.05)。痰湿壅盛证和阴阳两虚证TG相比差异有统计学意义(P<0.05),阴虚阳亢证与痰湿壅盛证相比,差异仍有统计学意义(P<0.05)。肝火亢盛证与痰湿壅盛证与正常组及阴阳两虚证TG比较差异有统计学意义(P<0.05);高血压病各证型中HDL在痰湿壅盛证下降最明显,且各证型与正常组比较均有下降,差异有统计学意义(P<0.05),痰湿壅盛证与肝火亢盛证和阴虚阳亢证相比差异有统计学意义(P<0.05)。LDL在中医各证型中阴阳两虚证升高明显,且与肝火亢盛证、阴虚阳亢证、正常对照组相比有统计学意义(P<0.05)。结论:(1)甘油三酯(TG)升高和HDL-C降低可以作为痰湿壅盛型辨证的客观化指标。(2)LDL-C升高可以作为阴阳两虚型辨证的客观化指标。(3)高血压病中医各证型中,痰湿壅盛型患者患动脉粥样硬化(AS)和冠心病(CHD)的风险性最高。

Objective:To study the relationship of lipids and essential hypertension in Southern Sichuan area.Methods:140 essential hypertension patients and 40 normal blood pressure persons in Luzhou of Sichuan province were detected to compare their blood pressures and lipids.Results:In the four types of high blood pressure syndromes above,TG of the liver-fire hyperactivity type,yin deficiency and yang preponderance type,excessive phlegm type and normal people showed a significant difference statistically(P<0.05).The TG comparison of the excessive phlegm and the yin and yang deficiency had asignificant difference statistically(P<0.05).The TG comparison of the yin deficiency and yang preponderance and the excessive phlegm also had a significant difference statistically(P<0.05).LDL of the yin and yang deficiency in the all syndromes increased significantly,and the comparison of the liver-fire hyperactivity,the yin deficiency and yang preponderance and normal people had statistical significance(P<0.05).Conclusion:A.The increase of TG and reduction of HDL-C can be used as objective indices of phlegm-dampness type.B.The rising of LDL-C can be used as objective indices of yin and yangd eficiency.C.The patients of the excessive phlegm have a risk of AS and CHD in hypertension of TCM syndromes.