艾滋病暴露前用药优先干预人群筛选研究

Research on pre exposure prophylaxis(PrEP) for preferred intervention crowd screening

目的:筛选艾滋病暴露前用药(Preexposure prophylaxis,PrEP)扩大规模临床试验的适宜高危人群。方法:采用Topsis法对高危人群的9个指标基于PrEP必要性和可行性两个层面进行评估。结果:男性性行为者为最佳目标人群,艾滋病病毒(Human immunodeficiency virus,HIV)感染者配偶次之,女性性工作者为较不适宜人群。结论:评价结果符合实际情况,选择的评价指标代表性较好,结果可靠。

Objective：To screen the appropriate high-risk group for the expanded scale clinical trials of PrEP.Methods：The high risk groups＇9 indexes,which were based on the necessity and feasibility of PrEP,were assesde with Topsis.Results：MSM are the best target population,PARs are in the second,and FSWs are Less appropriate.Conclusion：The results accord with actual situation,and the representative to the chosed evaluation indexes is better and reliable.