正常血压糖耐量低减患者尿白蛋白排出率相关因素分析

The Analysis of the Factors Related to Urinary Albumin Excretion Rate(UAER)in Normotensive Patients with Impaired Glucose Tolerance

对 2 17例正常血压糖耐量低减 (IGT)患者及 16 0例正常人尿白蛋白排出率 (U AER)进行了测定 ,且应用多元逐步回归分析法对正常血压 IGT患者 U AER可能的危险因素进行了探讨。结果显示 IGT患者 U AER明显高于正常对照组 ,且 IGT患者的收缩压 (SBP)、舒张压 (DBP)、体质指数 (BMI)、腰臀比值 (WHR)及血清服糖后 2 h胰岛素均明显高于对照组 ,而胰岛素敏感指数 (ISI)明显低于正常对照组。多元逐步回归分析显示 IGT患者 U AER仅与 SBP呈显著正相关。提示血压正常的 IGT患者 U AER增加 ,且伴有多种心血管疾病的危险因子增加。

To investigate the changes of UAER and its related factors in normotensive patients with impaired glucose tolerance(IGT),the UAER and its various factors were detected both in 217 IGT patients with normal blood pressure(NBP) and 160 healthy persons as a control group.The correlation analysis was performed by multiple stepwise regression.The results showed that UAER,systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),waist hip ratio(WHR) and serum 2 hours insulin of the IGT group were higher than those of normal control,but insulin sensitivity index(ISI) was lower than that of control.The factor,which was positively correlated with UAER of IGT group,was only SBP.