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冠心病冠状动脉病变程度与临床生化指标相关性研究 被引量:2

Study of Correlation between Clinical Biochemical Items and Coronary Heart Disease's Severity
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摘要 目的:研究不同类型冠心病生化指标与冠状动脉病变程度相关性。方法:检测稳定型心绞痛、不稳定型心绞痛、急性心肌梗死和正常对照组研究对象血压、BG、TC、TG、LDL、HDL、LP(a)和hs-CRP水平,分析其与Gensini积分的相关性。结果:冠心病组患者BMI指数、血压、BG、TC、TG、LDL和LP(a)均高于对照组(P<0.05),TC、TG、LDL、HDL、Gensini积分和hs-CRP在冠心病各组间的差异具有统计学意义(P<0.05)。BMI指数、血压、TC、TG和LDL在冠心病组患者中与Gensini积分正相关(P<0.05),HDL呈负相关(P<0.05);hs-CRP在SAP组和UAP组患者中与Gensini积分无相关性,在AMI组正相关(P<0.05)。BMI指数、TC、TG、LDL、LP(a)和hs-CRP是Gensini积分的危险因素,HDL为保护因素。结论:BMI指数、血压、TC、TG和LDL与冠状动脉病变程度正相关,可作为其评估的临床生化指标。 Objective:To study the correlation between clinical biochemical items and coronary heart disease' s severity. Methods:Blood pressure(BP),blood glucose(BG),total cholesterol(TC),triglyceride(TO),low density lipoprotein(LDL),high density lipoprotein(HDL),lipoprotein a(LP(a)) and high sensitivity c reaction protein(hs-GRF) were detected in patients with coronary heart disease and healthy people.Results:BMI index,BE BG,TC,TG,LDL and LP(a) in patients with coronary heart disessse were higher than control group(P0.05).TC.TG,LDL,HDL,Gensini score and hs-CRP in patients with coronary heart disease wete statistics different (P0.05).BMI index,BP,TC,TG,and LDL correlated positively with Gensini score in patients with coronary heart disease,while HDL was negative.BMI index,TC,TG,LDL,LP(a) and hs-CRP were risk factors for Gensini score.Conclusion:BMI inc.ex,BP,TC,TG and LDL correlated positively with coronary heart disease' s severity and they could be severed as evaluation items for coronary heart disease.
出处 《中国医药导刊》 2011年第12期2034-2035,共2页 Chinese Journal of Medicinal Guide
关键词 冠心病 GENSINI积分 临床生化指标 病变 Coronary heart disease Gensini score Clinical biochemical item Severity
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