辛伐他汀辅助治疗不稳定性心绞痛的临床疗效观察

Simvastatin Treatment of Unstable Angina Secondary Clinical Efficacy

目的:观察辛伐他汀辅助治疗不稳定性心绞痛的临床疗效。方法:选取我院自2007年3月～2010年5月收治的100例不稳定性心绞痛患者,随机分为观察组(辛伐他汀治疗组)和对照组(常规治疗组)各50例,连续治疗3个月后比较两组患者的治疗效果。结果:观察组显效32例,有效17例,无效1例,总有效率为98.0%;对照组显效21例,有效20例,无效9例,总有效率为82.0%。两组比较差异显著(P<0.01),具有统计学意义。两组患者治疗期间出现恶心2例、头痛1例,经调整用药后消失,无其他明显不良反应发生。结论:辛伐他汀辅助治疗不稳定性心绞痛效果理想,可明显减少心绞痛发生率、缓解疼痛程度、改善心电图表现,值得临床推厂应用。

Objccrive：Simvastatin treatment of unstable angina secondary clinical efficacy.Methods：In our hospital from March 2007 - May 2010 treated 100 patients with unstable angina were randomly divided into two groups（simvastatin treatment group） and control group（conventional treatment group）,50 patients continuous treatment for 3 months after treatment of two groups were compared. Results：The markedly effective in 32 cases,effective in 17 cases,1 case,the total effective rate was 98.0%：control group,21 cases markedly effective in 20 cases,9 cases,total effective rate was 82.0%.The difference was significant P0.01）.with statistical significance. Two groups of patients with nausea during treatment in 2 cases,headache in 1 case,the adjusted disappeared after treatment,no other significant adverse reactions.Conclusion：Simvastatin treatment of unstable angina secondary effect of the ideal,can significantly reduce me incidence of angina,relieve pain,improve the ECG,is worthy of clinical application.