摘要
目的:探索建立兔无血预充体外循环术后成活模型的实验方法。方法:实验动物为12只纯种新西兰大白兔,经颈动、静脉插管,无血预充,建立体外循环模型,术后成活饲养。结果:术中及术后监测显示血红蛋白偏低,动脉血气多数偏酸,血压在正常范围。1只兔体外循环过程中因急性左心衰死亡,其余11只均成功建立体外循环并在术后成活饲养24小时。结论:闭胸兔体外循环术后成活模型建立简便可行。
Objective：To establish a cardiopulmonary bypass（CPB） model of rabbit.Methods：Twelve New Zealand rabbits were included in this experiment.The CPB without blood priming was established via carotid and jugular cannulation.The blood-gas analysis.blood pressure and Hb parameters were examined during and after CPB.Results：Durrag and after CPB.Hb was declined,but blood-gas analysis showed pH value was lower.The blood pressure was maintained at the normal levei.Only one rabbit died in the process of CPB due to acute left heart failure.Conclusion：？stablishment of rabbit closed chest cardiopulmonary bypass model was showed feasible and effective.
出处
《中国医药导刊》
2011年第12期2151-2152,共2页
Chinese Journal of Medicinal Guide
关键词
兔
体外循环
动物模型
术后饲养
Rabbit
Cardiopulmonary bypass
Animal Model
Postoperation raise
