期刊文献+

保山地区肝癌发病率与代谢综合征相关性研究

The Research of Correlation of Incidence of Liver Cancer and Metabolic syndrome in the Cases of BaoShan Area
下载PDF
导出
摘要 目的探讨代谢综合征与肝癌的相关性。方法采用病例对照的方法分析同时期住院的肝癌患者与肝癌合并代谢综合征患者的相关因素及差异。对比分析两组患者的体质指数、血糖、血脂、乙肝感染时间、发现肿瘤时间、肝硬变程度等方面的差异。结果肝癌合并代谢综合征组较肝癌组时间早,肝硬化程度较重。结论代谢综合征诱导肝硬化发生,促进了肝硬化进程,并加速了肝硬化向肝癌的转化。代谢综合征与肝癌发生有一定关系,积极控制代谢综合征对于防范肝癌及改善预后有一定作用。 Objective To study on the correlation between metabolic syndrome and hepatocellular carcinoma.Methods A case-control analysis were conducted to study the related factors and differences between hepatocellular carcinoma patients and hepatocellular carcinoma complicated with metabolic syndrome during the same inpatient period.Comparative analysis was used to investigate changes of body mass index,blood glucose,blood lipid,hepatitis B infection time,cirrhosis of the liver tumor of two groups of patients.Results The incident time,of patients with hepatocellular carcinoma complicated with the metabolic syndrome was earlier than patients with liver cancer,and the cirrhosis of the former was more severe than that of the later.Conclusion Metabolic syndrome may promote and accelerate the process of liver cirrhosis to hepatocellular carcinoma.There have been a certain relationship between metabolic syndrome and liver cancer,so active control of metabolic syndrome may be meaningful for the prevention and for improving the prognosis outcome of hepatocellular carcinoma.
出处 《四川解剖学杂志》 2011年第4期7-9,共3页 Sichuan Journal of Anatomy
关键词 相关性 肝癌 代谢综合征 Correlation Hepatocellular carcinoma Metabolic syndrome
  • 相关文献

参考文献6

  • 1赵金艳,高春芳.代谢综合征与肝癌流行病学研究进展[J].第二军医大学学报,2010,31(4):425-428. 被引量:7
  • 2张锦前,范小玲.慢性丙型肝炎与代谢综合征[J].世界华人消化杂志,2006,14(36):3482-3486. 被引量:16
  • 3Charette N,Leclercq IA.Why should the gastroenterologistbother about obesity?An oncologic point of view. Acta Gas-troenterol Belg . 2010
  • 4Welzel TM,Graubard BI,Zeuzem S,et al.Metabolic syndromeincreases the risk of primary liver cancer in the United States:astudy in the SEER-Medicare database. Hepatology . 2011
  • 5Jin X,Moskophidis D,Mivechi NF.Heat shock transcriptionfactor 1is a key determinant of HCC development by regulatinghepatic steatosis and metabolic syndrome. Cell Metab . 2011
  • 6A Suriawinata,MI Fiel.Liver pathology in obesity. Seminars in Liver Disease . 2004

二级参考文献46

  • 1Katalin Jármay,Gizella Karácsony,András Nagy,Zsuzsa Schaff.Changes in lipid metabolism in chronic hepatitis C[J].World Journal of Gastroenterology,2005,11(41):6422-6428. 被引量:22
  • 2Fatty Liver and Alcoholic Liver Disease Study Group of the Chinese Liver Disease Association..非酒精性脂肪性肝病诊疗指南[J].中华肝脏病杂志,2006,14(3):161-163. 被引量:1513
  • 3Marrero C R, Marrero J A. Viral hepatitis and hepatocellular carcinoma[J]. Arch Med Res,2007,38:612-620.
  • 4Paradis V, Zalinski S, Chelbi E, Guedj N, Degos F, Vilgrain V, et al. Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: A pathological analysis[J]. Hepatology, 2009,49: 851-859.
  • 5Watanabe S, Yaginuma R, Ikejima K, Miyazaki A. Liver diseases and metabolic syndrome[J]. J Gastroenterol, 2008,43 : 509-518.
  • 6Farrell G C, Larter C Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis[J]. Hepatology, 2006, 43 (2 suppl 1 ) : S99- S112.
  • 7Reaven G M. Banting lecture 1988. Role of insulin resistance in human disease[J]. Diabetes, 1988,37 : 1595-1607.
  • 8Cowey S, Hardy R W. The metabolic syndrome: A high risk state for cancer[J]? Am J Pathol,2006,169:1505-1522.
  • 9Bosch F X,Ribes J, Diaz M, Cleries R. Primary liver cancer:worldwide incidence and trends[J]. Gastroenterology, 2004,127 (5 suppl 1):S5-S16.
  • 10Marrero J A,Fontana R J, Su G L, Conjeevaram H S, Emiek D M, Lok A S. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States [J]. Hepatology, 2002,36:1349 -1354.

共引文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部