脑钠肽及血管紧张素转化酶检测对胸腔积液的诊断价值

Value of BNP and ACE detection for diagnosis of pleural effusion

目的探索BNP及ACE活性变化对胸腔积液的诊断价值。方法选择确诊的90例胸腔积液病例,其中漏出液30例,肿瘤组30例,以及肺结核病组30例,常规胸膜穿刺并抽取胸腔积液检测,对3组患者的检测结果进行比较及统计学分析。结果结合胸腔积液、恶性胸腔积液及漏出液中,BNP及ACE活性明显不同,经统计学比较,组间差异具有统计学意义(P<0.05)。结论 BNP和ACE活性变化联合检测对渗出液及结核性和恶性胸腔积液的鉴别诊断具有一定价值,有助于临床胸腔积液性质的判断,对胸腔积液诊断及鉴别诊断具有一定的参考价值。

Objective To discuss the value of BNP and ACE activity changes for diagnosis of pleural effusion.Methods Ninty cases of pleural effusion patients were selected and divided into the transudate group,tumour group and pulmonary tuberculosis group,each group had 30 cases.Conventional pleural puncture was proceeded and pleural effusion was detected.The detection results of the three groups were compared and analyzed statistically.Results BNP and ACE activity were differences among combination pleural effusion,malignant pleural effusion and transudate,the differences were statistically significant（P 0.05）.Conclusion The combination detection of BNP and ACE activity has a certain value for differential diagnosis of transudate,tuberculosis and malignant pleural effusion,which can help to judge the property of pleural effusion in clinic and has a certain reference value for diagnosis and differential diagnosis of pleural effusion.