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氟伐他汀对不稳定性心绞痛患者高敏C反应蛋白及微量白蛋白尿的影响 被引量:1

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摘要 目的观察不稳定型心绞痛(UA)患者血清高敏C-反应蛋白(hsCRP)、微量白蛋白尿(MA)的变化及氟伐他汀对其影响。方法:将不稳定型心绞痛患者88例随机分为常规治疗组与氟伐他汀治疗组,两组均按不稳定型心绞痛治疗方法给予常规治疗,氟伐他汀治疗组另外服用氟伐他汀,同时设38例健康对照组。对照组及两治疗组于治疗前后检查高敏hsCRP、MA。结果:与对照组比较,常规治疗组、氟伐他汀治疗组患者hsCRP、MA水平明显升高(均p〈0.05);4周后,氟伐他汀治疗组hsCRP、MA水平与对照组比较均有不同程度的降低(均p〈0.05),而常规治疗组hsCRP、MA水平与对照组比较无明显变化(均P〉0.05)。结论:联合检测hsCRP水平和MA对患者发生不稳定型心绞痛有更重要的预测作用;氟伐他汀具有抑制冠心病患者炎症反应,减轻心肌损伤作用,可能是其改善冠心病患者预后的重要机制之一。
出处 《中国中医药咨讯》 2012年第4期4-6,共3页
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