摘要
目的:检测原发性高血压患者血栓前状态相关指标,探讨血栓前状态(prothrombotic state,PTS)与原发性高血压的关系。方法:定量检测80例原发性高血压患者及30例正常对照组的血液流变学指标、纤维蛋白原(fibrinogen,FIB)。结果:①高血压1和2级组FIB、血黏度高于正常对照组(P<0.05)。高血压1和2级组血小板聚集率显著高于正常对照组(P<0.01)。高血压3级组FIB高于正常对照组(P<0.05)。高血压3级组血黏度、血小板聚集率显著高于正常对照组(P<0.01)。高血压1和2级组与高血压3级组FIB、血黏度、血小板聚集率没有统计学意义(P>0.05)。②血浆黏度与FIB呈正相关(r=0.297,P<0.01)。结论:原发性高血压患者存在血栓前状态。
Objective：To detect the related indexes prothrombotic state in patients with essential hypertension,and discuss the relationship between prothrombotic state（PTS）and essential hypertension.Method：The blood rheology indexes and fibrinogen（FIB） were detected in 80 patients with essential hypertension and 30 cases of healthy controls.Result：①The expression values of FIB and blood viscosity in grade 1 and 2 hypertension were significantly higher than controls（P0.05）.And platelet aggregation rate in grade 1 and 2 hypertension were significantly higher than controls（P0.01）.The expression values of FIB in grade 3 hypertension were significantly higher than controls（P0.05）.And blood viscosity,platelet aggregation rate in grade 3 hypertension were significantly higher than controls（P0.01）.the FIB,blood viscosity,platelet aggregation rate were no significant in grade 1,2 group and grade 3 hypertension（P0.05）.②Plasma viscosity level has a positive correlation with FIB level（r =0.297,P0.01）.Conclusion：Prothrombotic state is present in patients with essential hypertension.
出处
《内蒙古医学杂志》
2012年第2期133-136,共4页
Inner Mongolia Medical Journal
