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红景天苷、白藜芦醇和人参提取物对中波紫外线诱导人二倍体成纤维细胞损伤的保护作用 被引量:2

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摘要 目的:探讨红景天苷、白藜芦醇及人参提取物不同时间处理对中波紫外线UVB诱导人胚肺二倍体成纤维细胞(2BS)损伤的保护作用。方法:采用UVB照射2BS细胞不同时间,将5μmol/L红景天苷、10μmol/L白藜芦醇及25μg/ml人参提取物提前2小时加入细胞或者于照射后加药,培养一定时间后采用MTT法测定细胞活力。结果:红景天苷和白藜芦醇于照射前加药或者照射后加药均能有效上调UVB照射后的2BS细胞活力(P<0.05),而人参提取物提前加药能有效逆转UVB照射后2BS细胞活力的下降(P<0.05),于UVB照射后给药则无此作用(P>0.05)。结论:三者均能有效保护2BS细胞,减少UVB诱导的损伤,红景天苷和白藜芦醇对细胞照射后的损伤修复可能具有一定的促进作用。
机构地区 浙江医院
出处 《浙江中医杂志》 2012年第4期252-254,共3页 Zhejiang Journal of Traditional Chinese Medicine
基金 卫生部科学研究基金项目从线粒体生物合成角度研究红景天苷干预衰老的分子机制 编号:WKJ2011-2-014
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