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EGFR表达与三阴性乳腺癌靶向治疗的相关性 被引量:9

Correlation of EGFR Expression and Targeted Therapy of Triple Negative Breast Cancer
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摘要 三阴性乳腺癌是指雌激素受体(ER)、孕激素受体(PR)以及人类表皮生长因子受体2亚型(HER-2)都阴性的乳腺癌,内分泌治疗和抗HER-2靶向治疗无效,易发生局部复发和远处转移,预后较差。表皮生长因子受体家族(EGFR)在肿瘤的发生发展中具有重要的作用,EGFR在三阴性乳腺癌中高表达,EGFR已经成为肿瘤分子靶向治疗的重要靶点。全文就EGFR表达与三阴性乳腺癌靶向治疗的相关性作一分析。
出处 《中国肿瘤》 CAS 2012年第4期281-284,共4页 China Cancer
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