临床727例次单采血小板输注效果分析

Analysis on the Effectiveness in 727 Times of Platelet Transfusion

为分析临床单采血小板输注效果及其影响因素,回顾性分析湘雅第三医院2010年9月至2011年5月进行单采血小板输注的254名患者的727例次输注资料,计算血小板计数增高指数(CCI)和血小板回收率(PPR)评价血小板输注效果,统计输注有效率,根据患者病症、输血次数、血型和脾肿大与否分组进行统计学比较。结果表明,727例次输注单采血小板有效456例次,占62.72%,以急性失血性贫血和慢性系统性疾病患者输注效果较为明显,尤其是慢性肾疾病(有效率为94.12%);脾脏肿大影响血小板输注效果(有效率仅为40.35%);血小板输注次数与输注效果呈负相关。结论:脾脏肿大和血小板输注次数是影响输注效果的因素。

This study was purposed to analyze the efficiency of platelet transfusion and to explore factors influencing platelet transfusion efficiency.727 times of platelets transfusion in 254 patients in The Third Xiangya Hospital from September 2010 to May 2011 were analyzed retrospectively.Moreover,according to symptoms,times of platelet transfusion,blood types and splenomegaly,the corrected count of increment（CCI） and percentage of platelet recovery（PPR） were calculated for evaluation of platelet transfusion efficiency.The results showed that there were 456 effective transfusions out of 727 transfusions（62.72%）.Among them,the therapeutic effect of platelet transfusion for patients with acute blood loss anemia and chronic systemic diseases was relatively obvious,specially for chronic renal disease,the effective efficiency of them was 94.12%.The patients with splenomegaly showed a significant impact on platelet transfusion efficiency（41.07%）.Analysis found that the frequency of platelet transfusion negatively correlated with transfusion efficiency.It is concluded that the transfusion frequency and splenomegaly are factors influencing the transfusion efficiency.