抗抑郁药氟西汀和心理护理在癌症三阶梯止痛中的运用体会

Antidepressants Fluoxetine and Psychological Care for Cancer in the Three-step Ladder Analgesic Application and Experience

目的探讨氟西汀和心理护理在癌症三阶梯止痛中的作用。方法对我科2009年7月至2011年9月98例伴有疼痛的中晚期癌症患者在三阶梯止痛药物治疗的基础上,是否联合氟西汀治疗和心理护理分为三组,于治疗前及治疗6周末采用VAS评分法对疼痛程度评定和疗效的判断,采用SDS评分对各组间抑郁状态进行比较。结果三组止痛治疗前VAS评分无显著性差异;治疗6周后:联合氟西汀治疗组一和联合氟西汀、心理护理治疗组二的VAS评分和SDS评分均明显低于对照组,且治疗组二较治疗组一SDS评分明显降低,并有统计学意义。结论氟西汀治疗及有效的心理护理措施,可降低中晚期癌症患者VAS疼痛评分和SDS评分,提高疼痛的治愈率。

Objective To observe the effect of fluoxetine and psychological carefor enhancement of three-step ladder analgesia.Methods 98 patients from July 2009 to September 2011 with pain in advanced cancer to receive three-step ladder analgesia treatment were devided into three groups according to whether the combined fluoxetine treatment and psychological care,using VAS score assess the degree of pain and judge curative effect in the pretherapy and after 6 weeks of treatment,using SDS scores for depression among the groups were compared.Results Three groups of pre-treatment VAS score was no significant difference;after 6 weeks： treatment group I combined fluoxetine treatment,and treatment group II combined fluoxetine and psychological care VAS scores and SDS scores were significantly lower than the control group,and treatment group II SDS score was significantly lower compared with group I,and have statistically significant.Conclusion Fluoxetine treatment and effective psychological care in patients with advanced cancer can be reduced VAS score and SDS score,improve the recovery rate of pain.