培哚普利与卡托普利治疗原发性高血压的临床对比分析

Analysis of Perindopril and Captopril in the Treatment of Essential Hypertension Compared

目的对比分析原发性高血压病患服用卡托普利和培哚普利的临床治疗作用。方法整理我院59例2010年12月至2011年10月原发性高血压病患资料,回顾分析服用卡托普利(一组,28例)和培哚普利(二组,31例)的两组病患血压情况(包括动态监测和偶测结果)及用药不适症状。结果二组服药后偶测血压的收效病患比例大于一组,P<0.05偶测差异有意义;二组服药后动态监测血压的收效病患比例大于一组,P<0.05动态监测差异有意义;一组出现用药不适症状的病患比例大于二组,P<0.05不适症状差异有意义。结论原发性高血压病患服用卡托普利的临床治疗作用没有服用培哚普利的治疗作用明显,且后者更安全,适合广泛应用。

Objective Comparative analysis of patients with essential hypertension captopril and perindopril on the clinical therapeutic effect.Methods 59 cases of hospital order in December 2010 October 2011 patients with essential hypertension data,retrospective analysis of captopril（a group of 28 patients） and perindopril（B group,31 patients） and two groups of patients with blood pressure（even including dynamic monitoring and measuring the results） and medication symptoms.Results The two groups even after taking the blood pressure is more effective than the proportion of patients with a group,P〈0.05 significant difference even measured;the two groups after taking the dynamic monitoring of blood pressure is more effective than the proportion of patients with a group,P〈0.05 significant differences in dynamic monitoring;one group of drugs is greater than the proportion of patients with symptoms of the two groups,P〈0.05 significant differences in symptoms.Conclusion Patients with essential hypertension clinical captopril treatment did not take the role of perindopril treatment significantly,and the latter more secure,suitable for wide application.