重症监护病房呼吸机相关性肺炎病原学以及耐药性分析

Intensive Care Unit Ventilator-Associated Pneumonia Etiology, and Drug Resistance

目的:探讨重症监护病房呼吸机相关性肺炎病原学以及耐药性。方法:对我院2007年2月-2011年7月ICU内出现呼吸机相关性肺炎的患者99例作为研究对象,并对取痰液标本进行病原学以及耐药性分析。结果:革兰阴性菌的检出明显高于其他菌属,在G-杆菌中铜绿假单胞菌以及大肠埃希菌最为常见,G+球菌中以金黄色葡萄球菌以及肺炎链球菌最为常见;所有菌属均对常规抗菌药物有一定的耐药性,但其对万古霉素的敏感性仍然较高。结论:加强对ICU呼吸机相关肺炎进行分离致病菌并对其进行耐药性检测,以指导合理使用抗菌药物,有助于改善患者预后。

Objective： To investigate the intensive care unit ventilator-associated pneumonia etiology,and drug resistance.Methods： The hospital in February 2007 July 2011 appear in ICU ventilator-associated pneumonia in patients with 99 cases for the study,and spu-tum specimens of the etiology and to take drug resistance.Results： The detection of Gram-negative bacteria was significantly higher than other species,the G-bacteria Pseudomonas aeruginosa and Escherichia coli is the most common,G＋cocci Staphylococcus aureus and Streptococcus pneumoniae is the most common;all species are on conventional antibiotics have some resistance,but its sensitivity to vancomycin remains high.Conclusion： To strengthen the ICU ventilator-associated pneumonia pathogens were isolated and its resistance testing to guide the rational use of antibiotics,help to improve the prognosis of patients.