饥饿后再进食人群动脉血压的变化特点

The changes of artery blood pressure in people fed after being starving

目的总结饥饿后再进食人群动脉血压的变化特点，探讨人体在特殊生理条件下的血压变化规律。方法回顾性分析某煤矿透水事故中113例获救者的血压资料，包括收缩压（SBP）、舒张压（DBP）及平均动脉压（mABP）。以不同时间点（天）为横坐标，相应时间点各指标均数为纵坐标，绘制各指标随时间的变化曲线，并分析血压昼夜节律变化及低血压事件的发生情况。结果获救初期血压水平较低，随着治疗时间延长，血压呈上升趋势并逐步趋于稳定，SBP、DBP与mABP随时间的变化差异均有统计学意义（均P〈0．05）。获救时及0．5d收缩压低于此后各时间点，0．5d收缩压低于获救时，差异均有统计学意义（均P〈0．05）；获救时、0．5、1及1．5d舒张压低于此后各时间点，差异均有统计学意义（均P〈0．05）；获救时、0．5及1．0d平均动脉压低于此后各时间点，差异均有统计学意义（均P〈0．05）。1—4d的SBP均为夜间高于日间，DBP均为日间高于夜间，差异均有统计学意义（均P〈0．05）。1～4d低血压事件的发生率≤2．655％，非必然事件。结论长期饥饿后再进食初期存在动脉血压波动，初期有一过性血压下降，且有血压的昼夜节律紊乱。

Objective To explore changes of arterial pressure in people who were fed after being starving. Methods The clinical date of 113 miners rescued from coal mine flooding accident was retrospectively investigated, including their systolic blood pressure （SBP）, diastolic pressure （DBP）, mean arterial pressure （mABP）. The curves of the changes were drawn with time points （day） as horizontal ordinate and mean of each index at corresponding time point as vertical ordinate. All data were analyzed by SPSS13.0 statistical analysis software and adapted two-sided Z test, repeated measures analysis of variance. Results The blood pressure level was low in the early days. It rose gradually and remained steadily along with treatment. Change trends of SBP, （P〈 0.05）. DBP on day 0, 0.5, 1, 1.5 were lower than that on day 2 （P〈 0.05）. mABP on day 0,0.5, 1 were lower than that on day 1.5 （P〈 0.05）. SBP on 0：00am was significantly higher than that on 9：00 am within the first 4 days of eating （P 〈 0.05）. In the first 4 days of eating period, hypotension cases were observed. Occurring rate of hypotension was ~2.655 %. Two-sided Z test showed that hypotension event was small probability. Conclusion In the early days of starvation and eating, blood pressure slightly declined and rose gradually with the treatment. Disturbance rhythm of blood pressure existed within the first 5 days.