护理干预对癌痛患者止痛治疗影响的Meta分析

Meta-analysis of nursing intervention effect treatment patients with cancer pain

目的综合评价护理干预对癌性疼痛患者止痛治疗的影响,为癌性疼痛治疗过程进行护理干预提供依据。方法通过计算机检索PubMed、Elsevie、Embase等数据库和中国生物医学文献数据库(CBM)、中国知网(CNKI)中1979年1月1日～2011年7月30日国内外公开发表的文献,使用Review Manager4.2.2软件进行数据分析和处理,选择服药依从性、止痛效果、副作用等3个指标进行Meta分析,选择危险度差值(RD)作为效应指标,对纳入研究进行异质性检验后,采用固定效应模型或随机效应模型进行综合定量分析。结果入选文献11篇,护理干预组与对照组癌性疼痛患者服药依从性、止痛治疗效果、副作用的发生情况等方面有显著性差异(P<0.05)。结论护理干预能提高癌性疼痛患者服药依从性,提高止痛效果,减少副作用的发生。

Objective To provide the foundation of intervention during analgesic treatment, the effect of nursing intervention on anal- gesic treatment to patients with cancer pain was evaluated. Methods Suitable literatures in recent 32 years were searched from Pubmed, Elsevie, Embase, Chinese Biomedical Literature Database （CBM）, China National Knowledge Infrastructure （CNKI） digital library by computer. Medicine-taking compliance, analgesic effect and side effect were analyzed by Review Manager 4.2.2 software. As effect in- dicator, risk difference （RD） values were chosen to test the consistency of selected literatures. Fixed effect model, which also called ran- dom effects model was used in quantitative analysis. Results 11 pieces of literatures met the enrolling criteria. There were significant differences （P〈0.05）between intervention group and control group in medicine -taking compliance ,analgesic and side effect. Conclusion Nursing intervention can increase medicine-taking compliance and analgesic effect, and reduce side effect.