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国产盐酸吡利霉素乳区注入剂治疗奶牛乳房炎的效果观察 被引量:1

Evaluation of the Efficacy of Domestic Pirlimycin on Treating Mastitis of Cows
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摘要 本试验通过与进口盐酸吡利霉素的对比,研究确定了国产盐酸吡利霉素对葡萄球菌、链球菌性乳房炎的治疗效果,旨在为药物的临床应用提供依据。结果表明,隐性乳房炎试验组和对照组的总有效率均为100%(12/12和10/10),治愈率分别为83.33%(10/12)和90%(9/10),平均用药次数为1.65次和1.5次;临床型乳房炎试验组的25mg组、50mg组、75mg组和对照组的总有效率分别为50%(5/10)、75%(10/12)、85.71%(12/14)和80%(8/10);治愈率为30%(3/10)、58.33%(7/12)、64.29%(9/14)和60%(6/10);平均用药次数为6次、4.9次、5.57次和5次。经卡方检验,试验组和对照组之间治愈率、有效率均无显著差异。可以得出国产盐酸吡利霉素对葡萄球菌和链球菌引起的隐性乳房炎和临床型乳房炎,均有良好的治疗效果。 The efficacy of domestic extended pirlimycin therapy regimens for treatment of intramammary infections by Streptococcus and Staphylococcus was evaluated in cows. Efficacy of pirlimycin therapy against subclinical mastiffs was 100% (12/12 and 10/10) for the treatment group and control group, and the cure rate was 83.3% (10/12) and 90% (9/10) respectively. The average treatment times were 1.65 and 1.5. There was no significant difference between them(P〉0.05). Efficacy of pirlimycin therapy against clinical mastiffs was 50% (5/10), 75% (10/12), 85.71% (12/14) and 80%(8/10) for 25mg, 50mg, 75mg and control group, respectively. The cure rate was 30%(3/10), 58.33% (7/12), 64.29% (9/14) and 60%(6/10). The average treatment times were 6, 4.9, 5.57 and 5. There was no significant difference among them. Results of this study indicated that domestic extended pirlimycin therapy was effective in eliminating intramammary infections caused by Streptococcus and Staphylococcus in lactating dairy cows.
出处 《中国奶牛》 2012年第7期27-30,共4页 China Dairy Cattle
基金 国家奶牛产业技术体系QARS-37
关键词 盐酸吡利霉素 乳房炎 奶牛 Pirlimycin Mastitis Dairy
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参考文献3

  • 1Gillespie BE,Moorehead H,Lunn P,et al.Efficacy of extended pirlimycin hydrochloride therapy for treatment of environmentalStreptococcus spp and Staphylococcus aureus intramammary infections in lactating dairy cows[J].Vet Ther,2002,3(4),373-80.
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  • 3Package Insert of PIRSUE Sterile Solution.Pharmacia&Upjohn Company.Kalamazoo,Michigan49001,USA.

同被引文献36

  • 1曲家华,冯万宇,周庆民.黑龙江西部地区奶牛临床型乳房炎病原菌分离鉴定及耐药性分析[J].中国革食动物科学,2012,32(5):53-54.
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  • 4Alkasir R, Liu X, Zahra M, et al. Characteristics of Staphylococ- cus aureus Small Colony Variant and Its Parent Strain Isolated from ChronicMastitis at a Dairy Farm in Beijing, China [J]. Mi- crob Drug Resist, 2013,19(2): 138-145.
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  • 7Momtaz H, Safarpoor Dehkordi F, Taktaz T, et al. Shiga Toxin- Producing Escherichia coli Isolated from Bovine Mastitic Milk: Serogroups, Virulence Factors, and Antibiotic Resistance Proper- ties [J].Scientific World Journal, 2012, ID618709. doi:10.1100/ 2012/618709.
  • 8Bagcigil AF, Taponen S, Koort J, et ol. Py,rali S.Genetic basis of penicillin resistance of S. aureus isolated in bovine mastitis[J]. Acta Vet Scand, 2012(23): 54-69.
  • 9Kumar Shukla S, Rao TS. Dispersal of Bap-mediated Staphylo- coccus aureus biofilm by proteinase K [J]. J Antibiot (Tokyo), 2013, 66(2): 55-60.
  • 10Tremblay YD, Lamarche D, Chever P, et ol. Jacques Mstaphylo- cocci isolated from the milk of Canadian farms to form biofilms [J].J Dairy Sci, 2013, 96(1):234-246.

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