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L-FABP在肾脏疾病中的研究进展 被引量：6

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摘要 肝型脂肪酸结合蛋白（liver-type fatty acid binding protein,L-FABP,FABP1）属于脂肪酸结合蛋白（fatty acid binding protein,FABP）家族的成员之一,是一组低分子量（14～15kD左右）的可以结合长链脂肪酸的高保守性胞质蛋白。
作者 王红盼 路晓光 李平
机构地区 北京中医药大学 中日友好医院临床医学研究所
出处 《中国中西医结合肾病杂志》 2012年第1期80-83,共4页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 国家自然科学基金资助项目(No.30973911)
关键词 L-FABP 肾脏疾病 肝型脂肪酸结合蛋白 PROTEIN 长链脂肪酸 胞质蛋白 低分子量 保守性
分类号 R692 [医药卫生—泌尿科学]
  • 相关文献

参考文献28

  • 1Chmurzynska A.The multigene family of fatty acid-binding proteins(FABPs):function,structure and polymorphism.J Appl Genet,2006,47(1):39-48.
  • 2He Y,Yang X,Wang H,et al.Solution-state molecular structure of apo and oleate-liganded liver fatty acid-binding protein.Bi-ochemistry,2007,46(44):12543-12556.
  • 3Gordon JI,Elshourbagy N,Lowe JB,et al.Tissue specific expres-sion and developmentalregulation of two genes coding for rat fatty acid binding proteins.J Biol Chem,1985,260(4):1995-1998.
  • 4Martin GG,Atshaves BP,Mcintosh AL,et al.Liver fatty acid-binding protein gene-ablated female mice exhibit increased age-dependent obesity.J Nutr,2008,138(10):1859-1865.
  • 5Murphy EJ.L-FABP and I-FABP expression increase NBD-stearate uptake and cytoplasmic diffusion in L cells.Am J Physi-ol,1998,275(2Pt1):G244-G249.
  • 6Wolfrum C,Buhlmann C,Rolf B,et al.Variation of liver-type fatty acid binding protein content in the human hepatoma cell line HepG2by peroxisome proliferators and antisense RNA af-fects the rate of fatty acid uptake.Biochim Biophys Acta,1999,1437(2):194-201.
  • 7Wolfrum C,Borrmann CM,Borchers T,et al.Fatty acid and hypo-lipidemic drugs regulate peroxisome proliferator-activated re-ceptors alpha-and gamma-mediated gene expression via liver fatty acid binding protein:asignaling path to the nucleus.Proc Narl Acad Sci U S A,2001,98(5):2323-2328.
  • 8Wang G,Gong Y,Anderson J,et al.Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells.Hepatol-ogy,2005,42(4):871-879.
  • 9Kamijo-Ikemori A,Sugaya T,Kimura K.Urinary fatty acid binding protein in renal disease.Clin Chim Acta,2006,374(1-2):1-7.
  • 10Maatman RG,Van Kuppevelt TH,Veerkamp JH.Two types of fatty acid-binding protein in human kidney.Isolation,charac-terization and localization.Biochem J,1991,273(Pt3):759-766.

同被引文献69

  • 1向礼芳,宋玉燕,邓建琼.uKIM-1和uL-FABP对脓毒症患者急性肾损伤诊断价值的临床研究[J].现代医学,2020(7):845-850. 被引量：5
  • 2陈佳兮,周君富,沈汉超.Oxidative stress and damage induced by abnormal free radical reactions and IgA nephropathy[J].Journal of Zhejiang University-Science B(Biomedicine & Biotechnology),2005,6(1):61-68. 被引量：4
  • 3林倩瑶.匹伐他汀可有效缓解糖尿病性肾病[J].国外医学情报,2006,27(3):38-38. 被引量：3
  • 4Smith JM, Stahlein OM, Munoz R, et al. Contributions of the Transplant Registry: The 2006 Annual Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) [J]. Pediatr Transplant, 2007 ,11( 4 ) : 366 - 373.
  • 5Klahr S, Morrissey J. Obstructive nephropathy and renal fibrosis [J]. Am J Physiol Renal Physiol,2002 ,283 (5) : F861 - F875.
  • 6Chevalier RL, Thornhill BA, Forbes MS, et al. Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy [J]. Pediatr Nephrol,2010 ,25 (4) :687 - 697.
  • 7Otsuka T, Tanaka A, Suemaru K, et al. Evaluation of the clinical application of cystatin C, a new marker of the glomerular filtration rate, for the initial dose - setting of arbekacin [J]. J Clin Pharm Ther,2008,33(3) :227 -235.
  • 8Lezaic V, Dajak M, Radivojevic O, et al. Cystatin C and serum creatinine as predictors of kidney graft outcome [J]. Int Urol Nephrol,2014 ,46(7) :1447 -1454.
  • 9Asilioglu N , Acikgoz Y , Paksu MS, et al. Is serum cystatin C a better marker than serum creatinine for monitoring renal function in pediatric intensive care unit[J].J Trop Pediatr,2012,58(6) :429 -434.
  • 10lriarte A, Arbildi P, La - Rocca S, et al. Identification of novel glutathione transferases in Echinococcus granulosus. An evolutionary perspective[J]. Acta Trop,2012,123(3) :208 -216.

引证文献6

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中国中西医结合肾病杂志
2012年 第1期

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