复方丹参注射液离子导入治疗前部缺血性视神经病变临床观察

A Clinical Research on Anterior Ischemic Optic Neuropathy Using Iontophoresis of Compound Danshen Injection

目的:观察复方丹参注射液离子导入治疗前部缺血性视神经病变的临床疗效。方法:将60例(62眼)前部缺血性视神经病变患者随机分为治疗组和对照组,两组患者均给予甲强龙静滴和一般辅助治疗,治疗组在此基础上加用复方丹参注射液离子导入。10天为1个疗程,共观察3个疗程。观察治疗前后两组患者的视力、视野、眼底等的变化。结果:治疗组总有效率为96.7%,对照组总有效率为86.7%,两组之间的差别有统计学意义(P<0.05)。治疗组在视力、视野、眼底等方面的改变均优于对照组。结论:复方丹参注射液离子导入配合甲强龙静滴治疗能够显著改善前部缺血性视神经病变患者的临床症状,提高视力,改善视野,减轻视乳头的水肿。

Objective：To observe clinical effect on treatment of anterior ischemic optic neuropathy（AION）using iontophoresis of compound Danshen injection.Method：60 patients（62 eyes）with AION randomly were divided into treatment group and control group.All patients were given intravenous methylprednisolone and the general adjuvant therapy.The treatment group on this basis plus iontophoresis of compound Danshen injection.10 days for a course,three courses were observed.Observed two groups of patients before and after treatment visual acuity,fundus,visual field and other changes.Result：The total effective rate was 96.7% in the treatment group and 86.7% in the control group,and there was a statistically significant difference in efficacy between the two groups（P〈0.05）.The changes in visual acuity,fundus,visual field of the treatment group are superior to the control group.Conclusion：Iontophoresis of compound Danshen injection with intravenous methylprednisolone can significantly improve clinical symptoms of AION patients,improve visual acuity and visual field,reduce the optic nerve edema.