APACHEⅡ评分与血清白蛋白在AECOPD合并呼吸衰竭中的应用研究

Value of APACHEⅡ and blood serum album in COPD patients with respiratory failure

目的探讨急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分和血清白蛋白(ALB)在慢性阻塞性肺疾病急性加重期(AECOPD)合并呼吸衰竭患者中的应用价值。方法将121例AECOPD合并呼吸衰竭患者根据是否机械通气分为机械通气组43例和非机械通气组78例;根据ALB水平分为正常ALB组45例和低ALB组76例。检测(计算)并比较不同分组患者的ALB水平(APACHEⅡ评分),并对两者进行相关性分析。结果机械通气组ALB水平低于非机械通气组,APACHEⅡ评分高于非机械通气组;低ALB组平均住院时间为(15.4±3.5)d,长于正常ALB组的(10.2±3.1)d,差异均有统计学意义(P<0.05)。APACHEⅡ评分与ALB呈负相关。结论 APACHEⅡ评分与ALB均可作为预测AECOPD合并呼吸衰竭患者机械通气的指标。

Objective To explore the value of APACHEⅡ and blood serum album in patients with respiratory failure.Methods 121 cases of AECOPD patients with respiratory failure mechanical ventilation were randomly divided into mechanical ventilation group with 43 cases and non mechanical ventilation with 78 cases;according to the ALB level they were divided into the normal ALB group with 45 cases and low ALB group with 76 cases.ALB level（APACHEⅡscore） were detected in different subgroups,and correlation were analyzed.Results ALB level in Mechanical ventilation group was lower than that in mechanical ventilation group,APACHEⅡscore was higher than non mechanical ventilation group;the average hospitalization time low ALB group was（15.4 ＋3.5） d,longer than the that in normal ALB group [（10.2 ＋3.1） d],the differences were statistically significant（P0.05）.APACHEⅡscore was negatively correlated with ALB.Conclusion Both APACHEⅡscore and ALB can be used as a predictor of AECOPD complicated with respiratory failure with mechanical ventilation index.