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亚砷酸、维生素C联合化疗治疗老年性多发性骨髓瘤的临床分析

Clinical analysis of arsenious acid,vitamin C combination chemotherapy in elderly multiple myeloma
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摘要 目的多发性骨髓瘤的治疗已取得不少进展,20世纪60年代引用美法仑治疗MM至今,有效率仅40-50%,完全缓解率仅5%,近年来,许多新的治疗方法已经应用于临床。方法我院60例老年性MM患者均采用亚砷酸、维生素C联合化疗治疗,观察疗效。结果部分缓解19例,进步27例,无效14例;毒副作用主要为肝损害,应用保肝药物2周内可恢复正常。结论亚砷酸对于老年性多发性骨髓瘤具有良好疗效。 【Objective】 There has been much advancement about the therapy of multiple myeloma.From 1960s to today,quoting Melphalan for MM,the effective power is only 40-50% and the complete remission rate is only 5%.In recent years,many new treatments have been used to clinical.【Methods】 There are 60 senile patients with MM in our hospital to use arsenic trioxide 、vitamine C and combined chemotherapy,to observe the curative effect.【Results】 Partial remission 19,progress 27,invalid 14;the main toxic side effect is hepatic lesion,and it can become normal within 2 weeks after using liver aids.【Conclusion】 Arsenic trioxide has favorable curative effect for elderly multiple myeloma.
作者 李哲 李斌
出处 《中国医学工程》 2012年第1期31-32,共2页 China Medical Engineering
关键词 亚砷酸 维生素C 多发性骨髓瘤 arsenic trioxide vitamine C multiple myeloma
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