三门峡市2009年-2010年度手足口病病原体检测分析

Analysis and detection of Hand-foot-mouth diseases pathogen in Sanmenxia in 2009-2010

目的:对2009年-2010年三门峡地区临床诊断为手足口病病例进行病原体检测,为该病的预防和诊断治疗提供依据。方法:临床诊断为手足口病病例的260份粪便样本,采用RT-PCR检测病原体核酸,并结合流行病学资料予以分析。结果:共检测260份标本,阳性195份。其中EV71型92例,CoxA16型51例,其他肠道病毒52例。时间分布上病例高发期主要在3月-6月份,4月份达到顶峰,人口密集地区阳性率高,年龄主要在4岁以下,男孩标本数多于女孩,但女孩阳性率高于男孩。结论:2009年-2010年我市发生的手足口病主要由EV71和CoxA16型病毒引起。

Objective：To investigate the pathogenic diagnosis of the Hand-foot-mouth disease（HFMD） in Sanmenxia in 2009-2010,which may provide reference for prevention and clinical treatment of this disease.Methods：Two hundred and sixty specimens were collected from clinically diagnosed cases with HFMD and determined by RT-PCR with epidemiological analysis.Results：Among 260 specimens,195 were positive（75%）,serotyping of EV71,CoxA16 and other enterovirus were 47.18%,26.15%,26.67% respectively.Most cases occurred from March to June,the peak was found in April.The high positive rate was found in the densely populated region,0~4 years old children were main population.The cases of boys were more than girls,but the positive rate of girls was higher than boys.Conclusion：The main pathogens of HFMD in Sanmenxia during 2009 and 2010 were EV71 and CoxA16,which should paid more attention in the surveillance and control of the HFMD.