快速康复外科在腹腔镜结直肠癌根治术围手术期应用疗效的荟萃分析

Efficacy of fast-track surgery for laparoscopic surgery patients with colorectal cancer:meta-analysis and systematic review

目的:荟萃分析快速康复外科(FTS)在腹腔镜结直肠癌根治术中的应用疗效。方法:检索Pubmed、EMBASE、Cochrane Library、中国知网、万方数据库和维普数据库发表的FTS在腹腔镜结直肠癌根治术中疗效的文献,采用RevMan5.0软件进行统计分析。结果:9篇文献纳入分析,共纳入患者925例,试验组481例,对照组444例。FTS能缩短术后住院时间,加权均数差为-2.50(95%CI:-4.13,-0.87),P<0.0001;减少术后并发症,相对危险度(RR)为0.61(95%CI:0.47,0.78),P<0.0001;能缩短肠蠕动恢复时间(P<0.01);但在30d内再次入院率无统计学意义,RR为1.33(95%CI:0.78,2.25),P=0.29。结论:FTS在腹腔镜结直肠癌根治术中能降低术后并发症,缩短术后住院时间,有利于患者康复。

Objective To analyze the efficacy of fast-track surgery （FTS） in the treatment of laparoscopic surgery （LS） patients with coloreetal cancer by meta-analysis. Methods Searched PubMed, EMBASE, the Cochrane Library, Wanfang data, CNKI and Vip data. Controlled trails reported efficacy of FTS of LS in patients with colorectal cancer were collected and analyzed by using RevManS.0. Results Totally, 9 reports involving 925 colorectal cancer patients were enrolled in this study. The FTS group had shorter postoperative length of hospital stays and decreased morbidity rate of postoperative complication .Significant differences were found between the FTS group and the control group （P 〈 0.000 1 ）. There was no significant difference in the rate of readmission between the FTS group and the control group （P = 0.29）. Conclusions FTS can decrease the postoperative length of hospital stays and improve the effect of LS patients with colorectal cancer.