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子宫内膜癌表皮生长因子受体及其靶向治疗的研究进展 被引量:4

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摘要 子宫内膜癌是女性生殖系统最常见的恶性肿瘤之一,目前尽管针对子宫内膜癌的治疗方法和技术不断发展,但对晚期和复发的子宫内膜癌治疗仍为棘手。表皮生长因子受体(epidermalgrowthfactorreceptor,EGFR)是一种跨膜受体型酪氨酸激酶,其介导的信号转导通路参与多种肿瘤的发生发展.研究表明,其在子宫内膜癌中有过表达.并且与子宫内膜癌的发生、发展、侵袭等密切相关,是目前研究较多的肿瘤靶向治疗分子。现就国内外对EGFR及其靶向治疗在子宫内膜癌中的研究进展做简要综述。
作者 张雷英 傅芬
出处 《实用医学杂志》 CAS 北大核心 2012年第8期1371-1373,共3页 The Journal of Practical Medicine
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