摘要
由于表皮是外界与体内的屏障,因此无针注射喷射速度和初始滞止压力必须达到穿透表皮临界值。通过具体建立其穿透前变形的数学模型并结合其破裂过程,计算在0.1mm表皮厚度和喷嘴口径100～340μm下的射流穿透表皮的临界初始速度及滞止压力。并与已知数据比对来验证计算过程可靠性,而为无针注射器的设计提供一定的理论依据。
Needle-free injection is a new method of medicine injection into human body by a high velocity jet.Epidermis is the obstacle between the body and the outside enviroment,so the injection velocity and the initial stagnation pressure of different nozzles must be achieved at a certain value which can penetrate the epidermis rightly.When the epidermis is at the depth of 0.1mm and the nozzle diameter is between 100 μm and 340 μm,the velocity and the pressure can be figured out by setting up the mathematical model of the deforming and its crack,which can support to design the needle-free injection device by verify their reliability through contracting them with the data achieved already.
出处
《机械与电子》
2012年第4期12-14,共3页
Machinery & Electronics
基金
湖北省科技攻关计划招标项目(2006AA304A06)
关键词
无针注射
表皮穿透
起始速度
滞止压力
needle-free injection
epidermis penetration
initial velocity
stagnation pressure
