利用文本挖掘技术分析慢性盆腔炎的用药规律

Exploring the Association Rules of Chinese Patent Medicine and West Medicine for Chronic Pelvic Inflammation with Text Mining Technique

目的:利用文本挖掘技术探索西药、中成药对慢性盆腔炎(chronic pelvic inflammation,CPI)的治疗规律。方法:在中国生物医学文献数据库(CBM)中收集治疗CPI的相关文献,运用大型数据库(SQL)对数据进行处理,结合人工降噪,分析西药、中成药对CPI的治疗用药规律。结果:甲硝唑、替硝唑、氧氟沙星、庆大霉素、地塞米松等西药依次为治疗CPI文献中出现的高频药物。妇科千金片、康妇消炎栓、桂枝茯苓丸、千金散等依次为治疗CPI文献中出现的高频药物。同时也发现西药、中成药联合治疗CPI的一些规律。结论:利用文本挖掘的方法,从文献报告频数方面呈现了西药、中成药治疗CPI的用药规律,尤其是西药、中成药联合应用很值得进一步的研究。

Objective： To mine the association rules of Chinese patent medicine and west medicine used for chronic pelvic inflammation.Method： Transfered XML type data sets to the structured database of Microsoft SQL Server and visualized them into different graphs by software Excel and Cytoscape.Result： The results suggested that metronidazole,tinidazole,ofloxacin,gentamicin,and dexamethasone were the commonly used west medicine.Gynecologic Qianjin tablets,Kangfu Antiphlogistic Suppository,Guizhi Fuling bolus,and Qianjin powder are of the core Chinese patent medicine frequently used for chronic pelvic inflammation.Conclusion： The use of text mining methods,From the frequency reported in the literature has shown the Western medicine,Chinese medicine treatment of CPI＇s drug laws,especially in Western medicine-Chinese medicine combin were worth further study.