94例脑干胶质瘤MRI影像与病理分级的关系分析

Analysis of MRI and pathologic features of 94 cases of brainstem gliomas

目的探讨脑干胶质瘤的MRI影像学特点及其与病理分级的关系。方法回顾性分析经手术治疗并有明确病理诊断的94例脑干胶质瘤的临床资料，包括MRI及病理资料，并对相关变量进行统计检验，判断该变量与病理分级的关系。结果脑干胶质瘤直径大小（P=0．029）、是否跨脑干轴位中线生长（P=0．016）、有无坏死灶（P〈0．000）、囊变（P=0．004）以及对基底动脉包绕（P=0．001）在高、低级别胶质瘤之间的分布差异有统计学意义。结论脑干胶质瘤是一类异质性肿瘤，术前根据肿瘤直径大小、是否跨脑干轴位中线生长，囊变、坏死及基底动脉包绕，可在一定程度上判断脑干胶质瘤恶性程度，指导判断预后。

Objective To study the MRI and pathologic features of brainstem gliomas. Methods All 94 patients underwent surgical operation. MRI and pathology were accessed using the ehi - squared statistic in all patients with hrainstem gliomas. Results The grading of brainstem gliomas was related with tumor diameter（ P = 0. 029）, whether crossing mideourt line （ P = 0. 016） , necrosis of tumor （ P 〈 0.000） , cystic degeneration （ P = 0.004） and basilar artery engulfment （ P = 0.001 ）. Conclusions Brainstem glioma is regarded as a kind of heterogeneous tumor that could be distinguished by age of onset, clinical and radiological presentation and biological behavior. The grading of brainstem gliomas and prognosis could be predicted partially according to the tumor diameter , presence or absence of crossing midcourt line, necrosis of tumor, cystic degeneration and basilar artery engulfment.