期刊文献+

昆明小鼠乳腺不同发育时期Hex蛋白的免疫组织化学定位

下载PDF
导出
摘要 为了研究昆明小鼠乳腺发育4个时期即青春期、妊娠期、泌乳期和退化期的同源异型盒基因(Hex)蛋白表达规律及组织定位,试验采用免疫组织化学法进行检测。结果表明:昆明小鼠乳腺组织结构呈周期性变化,青春期至妊娠期Hex蛋白逐渐增加,泌乳期达到高峰,退化期逐渐下降至类似青春期水平;Hex蛋白主要定位于细胞质中,泌乳期在细胞核中也有少部分出现;昆明小鼠乳腺发育的4个阶段均有Hex蛋白表达,且与乳腺周期性的变化一致。说明Hex蛋白参与乳腺的发育和泌乳调控过程。
出处 《黑龙江畜牧兽医》 CAS 北大核心 2012年第5期50-52,共3页 Heilongjiang Animal Science And veterinary Medicine
基金 哈尔滨师范大学第五届大学生创新基金项目(20100074) 黑龙江省农业生物功能基因重点实验室开放课题(NXGJ-2009-004)
  • 相关文献

参考文献12

  • 1LEWIS B E. Homeosis: the first 100 Years[J]. Cell,2007,5 (2) : 505 -510.
  • 2WRIGHT T R F. Genetic regulatory hierarchies in development [ M ]. New York : Academic Press Ine, 1990.
  • 3ZAKANY J, GERARD M, FAVIER B, et al. Function equivalence and rescue among group II Hox gene products in vertebral patteming [ J], Dev Biology, 1996,176:325 - 328.
  • 4SCOTT M P. Vertebrate homeobox gene nomenclature [ J ]. Cell, 1992,71 : 551 -553.
  • 5MARTINEZ B J P,CLEMENTS M,THOMAS P,et al. The homeobox gene hexis required in definitive endodermal tissues for normal fore- brain, liver and thyroid formation [ J ]. Development, 2000, 127 : 2433 - 2445.
  • 6STEER P,O'ROURKE D,GHORASHI S,et al. Application of high- resolution melting curve analysis for typing of fowl adenoviruses in field cases of inclusion body hepatitis [ J ]. Aust Vet J,2011,89 (5) : 184 - 192.
  • 7CROMPTON M R,BARTLETT T L,MACGREGOR A D,et al. Iden- tification of a novel vertebrate homeobox gene expressed in haemato- poietic cells [ J ]. Nucleic Acids Res, 1992,20: 5661 -5667.
  • 8BEDFORD K, ASHWORTH A, ENVER T, et al. HEX:a novel ho- meobox gene expressed during haematopoiesis and conserved be- tween mouse and human[ J]. Nucleic Acids Res, 1993,21 : 1245 - 1249.
  • 9HROMAS R, RADICH J, COLLINS S. PCR cloning of an orphan ho- meobox gene ( PRH ) preferentially expressed in myeloid and liver cells [ J ]. Biochem Biophys Res Commun, 1993,195 : 976 - 983.
  • 10NEWMAN C S,CHIA F,KRIEG P A,et al. The Hex homeobox gene is expressed during development of the vascular endothelium: over- expression leads to an increase in vascular endothelial cell number [ J]. Mech Dev, 1997,66 : 83 - 93.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部