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上皮间叶转化及其在间叶源性肿瘤中的研究进展 被引量：4

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摘要 上皮间叶转化(epithelial mesenchymal transition,EMT)出现在各种生理和病理情况下,参与胚胎发生与器官发育、纤维化过程以及肿瘤的形成和转移。目前的研究使人们对EMT的分子机制有了一定的认识,EMT与肿瘤发生和转移间关系的研究对象较多集中于上皮源性的肿瘤和细胞系,而近年研究发现EMT也存在于间叶源性的肿瘤中,其分子调控机制与在上皮源性肿瘤中可能不同。本文就EMT的分子机制及其在间叶源性肿瘤中的研究进展做一综述。
作者 王翠翠 邹泓 刘春霞 齐妍 李锋
机构地区 石河子大学医学院病理学教研室/新疆地方与民族高发病重点实验室
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第4期429-431,共3页 Chinese Journal of Clinical and Experimental Pathology
基金 国家自然科学基金(81160322 81060209) 兵团青年科技创新资金计划(2011CB022)
关键词 间叶源性肿瘤 上皮间叶转化 分子机制
分类号 R730.262 [医药卫生—肿瘤]
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临床与实验病理学杂志
2012年 第4期

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