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趋化因子及其受体在病毒性疾病中的作用 被引量:1

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摘要 趋化因子(chemokine)是一类三维结构上相似,唯一的一类通过G蛋白偶联受体超家族起作用的细胞因子。趋化因子及其受体主要介导了细胞的定向移动,参与免疫细胞和器官的发育、免疫应答过程、病原体感染与清除、肿瘤形成和转移,此外近年来还报道趋化因子可扮演神经调质和细胞凋亡促进因子的角色,发挥广泛的生理和病理作用。
出处 《中华实验和临床病毒学杂志》 CAS CSCD 2012年第2期153-155,共3页 Chinese Journal of Experimental and Clinical Virology
基金 “863”项目(2007AA021107)
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  • 1Cocchi F, DeVico AL, Garzino-Demo A, et al. Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factors produced by CD8+ T ceils. Science, 1995, 270: 1811-1815.
  • 2Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature, 1996, 332:722-725.
  • 3Zeremski M, Petrovic LM, Talal AH. The role of chemokines as inflammatory mediators in chronic hepatitis C virus infection. J Viral Hepat,2007,14:675-687.
  • 4Guidotti LG, Chisari FV. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol, 2001,19:65-91.
  • 5Nattcnnann J,Zimmermann H,Iwan A, et al. Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C. Hepatology, 2006, 44: 945 -954.
  • 6Heydtmann M, Adams DH. Chemokines in the Immunopathogenesis of Hepatitis C Infection. Hepatology,2009, 49:676-688.
  • 7Helbig KJ, Ruszkiewicz A, Semendrie L, et al. Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation. Hepatology, 2004,39 : 1220-1229.
  • 8Soo HM, Garzino-Demo A, Hong W, et al. Expression of a full- length hepatitis C virus cDNA upregulates the expression of CC ehemokines MCP-1 and RANTES. Virology,2002,303:253-277.
  • 9Marra F, Romanelli RG, Giannini C, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology, 1999,29 : 140-148.
  • 10David MK,Peter MH. Fields Virology. 5th ed. 2007 ;572.

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