摘要
证据提示脂联素在卵巢分泌类固醇激素和胎盘发育中发挥了重要的作用。其不仅直接影响晚期卵泡的合成，还影响胰岛素与促性腺激素释放激素作用从而影响初始卵泡形成。脂联素通过多种信号途径对卵巢功能和胎盘形成具有潜在性的作用，为代谢及生殖相关疾病的病因学研究和治疗提供新的思路。
There is a strong support for a role played by adiponectin in the function of ovary and placenta. There is evidence of direct effects of adiponectin on the late stages of folliculogenesis, and additive interactions of adiponectin with insulin and gonadotropins in inducing periovulatory changes in ovarian follicles. Adiponectin has demonstrated a potential effect on ovarian function as well as a possible effect on the formation of placenta, via multiple mechanisms, providing new strategies for the etiology investigation, prevention and treatment of reproductive and related metabolic diseases.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2012年第4期347-350,共4页
Chinese Journal of Endocrinology and Metabolism
基金
上海市科委重点科技攻关项目（08411953000）
关键词
脂联素
脂联素受体
信号途径
卵巢功能
多囊卵巢综合征
Adiponectin
Adiponectin receptor
Signal pathway
Ovary function
Polycystic ovary syndrome
