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上海地区实验大小鼠肺支原体感染情况调查

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摘要 目的了解上海地区清洁级和SPF级实验大、小鼠肺支原体(Mp)的感染情况。方法采集动物血清、气管中段,分别利用分离培养法、PCR法和ELISA法进行Mp检测。结果仅SPF级实验大鼠培养法呈阴性,其它级别大、小鼠三种方法检测结果皆有阳性。培养法检测实验小鼠和大鼠阳性率分别为2.9%和20%,PCR法的阳性率分别为21.4%和27.2%,ELISA法的阳性率分别为6.0%和21.5%。结论上海地区清洁级和SPF级大鼠和小鼠中存在着不同程度的肺支原体感染。
出处 《实验动物与比较医学》 CAS 2012年第2期149-151,共3页 Laboratory Animal and Comparative Medicine
基金 上海市科学基金资助项目(08140901300)
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