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冠心病高危人群颈动脉内中膜离散度变化及相关因素 被引量：5

Investigate to the change of carotid intima-media thickness dispersion and the factors of influence in high risk population of coronary heart disease
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摘要 目的探讨冠心病高危人群颈动脉内中膜厚度的离散度变化及相关影响因素。方法利用计算机自动识别技术，以每一像素为长度，自动计算出颈动脉内中膜厚度的最大值（CIMT—max）、均值（CIMTmean）、标准差（CIMTSD）并与各种高危因素进行相关分析。结果CIMTmax、CIMTmean、CIMTSD在高危组分别为（0．810±0．101）、（0．631±0．090）、（0．091±0．070）mm，在对照组分别为（0．704±0．099）、（0．557±0．063）、（0．045±0．014）mm；CIMTmax在0．6、0．7、0．8mm时，高危组CIMTSD分别为（0．059±0．029）、（0．100±0．068）、（0．073±0．018）mm，对照组分别为（0．041±0．015）、（0．050±0．013）、（0．042±0．013）mm；CIMTmean在0．50～0．69mm时，高危组CIMTSD分别为（0．069±0．021）、（0．084±0．055）mm，对照组分别为（0．045±0．011）、（0．050±0．017）mm（P〈0．05）；CIMTSD与血清超敏c-反应蛋白、甘油三脂、糖化血红蛋白、总胆固醇、低密度脂蛋白，收缩压、舒张压、吸烟等危险因素的相关性较CIMTmax、CIMTmean更好。结论CIMTSD比CIMTmax、CIMTmean更能反映早期动脉粥样硬化。 Objective To investigate the change of Common Carotid Intima-Media Thickness dis- persion and the factors of influence. Methods A computer-based method was developed for automatic rec- ognition and calculation of intima-media thickness, The CIMTmax, CIMTmean, CIMTSD were automatical- ly given in all 261 receptors; the correlations among different influence factors were analysis. Results The date of CIMTmax, CIMTmean, CIMTSD respectively as （0. 810±0. 101）, （0. 631±0. 090）, （0. 091±0. 070） mm in high risk group is higher than that （0. 704±0. 099）, （0. 557±0. 063）, （0. 045 ±0. 014） mm in control group （P 〈 0. 01 ） ; The CIMTSD is significantly increased in high risk group than in control group （P 〈0. 05）, when two groups have the same CIMTmax （0. 6, 0. 7, 0. 8 mm） or CIMTmean （0. 50- 0. 69 mm） ; Pearson correlation analysis showed that CIMT-SD was positively correlated with HsCRP, TC, TG, LDL-C, SBP, DBP, Smoke. Conclusion CIMTSD may be a new parameters for diagnosing the early atherosclerosis of Carotid.
作者 金雅磊 王桦 程新耀
机构地区 武汉大学中南医院综合医疗科 武汉大学中南医院心功能室
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第5期958-960,共3页 Chinese Journal of Experimental Surgery
关键词 内中膜厚度 离散度 标准差 相关 Intima-media thickness Dispersion Standard deviation Correlation
分类号 R543.4 [医药卫生—心血管疾病]
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参考文献4

二级参考文献16

  • 1赵海光,付士军,蒋米尔.人腹主动脉瘤与动脉粥样硬化闭塞症基因表达谱差异的研究[J].中华实验外科杂志,2007,24(2):137-139. 被引量：9
  • 2Stary HC, Chandler AB, Dinsmore RE, et al. A definition of advanced types of atherosclerotic lesions and a histological classi- fication of atherosclerosis. A report from the committee on vascular lesions of the council on arteriosclerosis, american heart association. Circulation, 1995,92 : 1355- 1374.
  • 3Lamont D, Parker L, White M, et al. Risk of cardiovascular disease measured by carotid intima media thickness at age 49-51: lifecourse study[J]. British Medical Journal, 2000, 320(7 230): 273-278.
  • 4Wendelhag I, Liang Q, Gustavsson T, et al. A new automated computerized analyzing system simplifies readings and reduces the variability in ultrasound measurement of intima media thickness[J]. Stroke, 1997, 28(11): 2 195- 2 200.
  • 5Cheng D, Schmidt-Trucksass A, Cheng K, et al. Using snakes to detect the intimal and adventitial layers of the common carotid artery wall in sonographic images[J]. Computer Methods and Programs in Biomedicine, 2002, 67(1): 27-37.
  • 6Loizou C P, Pattichis C S, Pantziaris M, et al Snakes based segmentation of the common carotid artery intima media[J]. Medical and Biological Engineering and Computing, 2002, 45(1): 35-49.
  • 7Ceccarelli M, de Luca N, Morganella A. Automatic measurement of the intima media thickness with active contour based image segmentation[C]//Proceedings of IEEE International Workshop on Medical Measurement and Applications. Warsaw: [s. n. ], 2007:1 5.
  • 8Kass M, Witkin A, Terzopoulos D. Snakes: active contour models[J]. International Journal of Computer Vision, 1988, 1(4): 321-331.
  • 9Williams D J, Shah M. A fast algorithm for active contours and curvature estimation[J]. CVGIP: Image Understanding, 1992, 55(1): 14-26.
  • 10Cohen L D, Cohen I, Ceremade P I X. Finite-element methods for active contour models and balloons for 2-D and 3-D images[J]. IEEE Transactions on Pattern Analysis and Machine Intelligence, 1993, 15 (11): 1 131-1 147.

共引文献12

同被引文献29

  • 1穆玉明,吴伟春,唐琪,韩伟.糖尿病及其合并高脂血症对颈部动脉粥样硬化影响的超声研究[J].中国医学影像技术,2005,21(3):419-421. 被引量：25
  • 2傅照华,葛智平,石福彦,郑桂杰.颈动脉粥样硬化与冠状动脉狭窄程度关系的研究[J].心血管康复医学杂志,2006,15(5):441-445. 被引量：11
  • 3Sasaki J,Otonari T,Sawayama Y,et al. Double-dose pravastatin versusadd-on ezetimibe with low-dose pravastatin-effects on LDL cholesterol,cholesterol absorption, and cholesterol synthesis in Japanese patientswith hypercholesterolemia ( PEAS study ) [J]. J Atheroscler Thromb,2012,19(5) :485493.
  • 4Gandhi MJ. Does “ENHANCE” diminish confidence in ezetimibe[J]. J Assoc Physicians India,2008,56:665-666.
  • 5Moutzouri E,Liberopoulos EN,Tellis CC, et al. Comparison of theeffect of simvastatin versus simvastatin/ezetimibe versus rosuvastatinon markers of inflammation and oxidative stress in subjects with hyper-cholesterolemia [J]. Atherosclerosis, 2013,231 (1) :8-14.
  • 6Torimoto K,Okada Y,Mori H,et al. Efficacy of combination of Ezetimi-be 10 mg and rosuvastatin 2. 5 mg versus rosuvastatin 5 mg monotherapyfor hypercholesterolemia in patients with type 2 diabetes [J]. LipidsHealth Dis,2013,12(l) :137.
  • 7Deyama J, Nakamura T,Takishima I, et al. Contrast-enhanced ultra-sound imaging of carotid plaque neovascularization is useful for identi-fying high-risk patients with coronary artery disease[J] . Circ J,2013,77(6):1499-1507.
  • 8Zhu Y,Deng YB,Liu YN,et al. Use of carotid plaque neovasculariza-tion at contrast-enhanced US to predict coronary events in patientswith coronary artery disease[J]. Radiology ,2013,268( 1) *54-60.
  • 9Heo SH,Cho CH,Kim HO’et al. Plaque rupture is a determinant ofvascular events in carotid artery atherosclerotic disease : involvement ofmatrix metalloproteinases 2 and 9[J]. J Clin Neurol,2011,7(2) :69-76.
  • 10Lorenz MW, Markus HS, Bots ML, et al. Prediction of clinical cardiovascular events with carotid intima-media thickness: A systematic review and meta-analysis. Circulation, 2007,115(4):459-467.

引证文献5

二级引证文献45

中华实验外科杂志
2012年 第5期

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