摘要
提出了一种心肌细胞电生理模型的建模仿真方法。通过借助Hodgkin-Huxley模型对单个心肌细胞建立细胞膜的等效电路模型,利用四阶Rouge-Kutta算法,研究并分析了心肌细胞膜内外离子电流及电位差变化。然后用C语言完成了对细胞膜等效电路模型的编程,利用Matlab软件平台进行了计算机仿真,得到了心肌细胞电生理学模型在不同刺激下的仿真实验结果。
A modeling and simulation methods of electrophysiological model of myocardial cells were proposed.Based on the Hodg-kin-Huxley model,equivalent circuit model of the rat＇s single cardiac muscle cell was built.Using fourth-order Rouge-Kutta algorithm,internal and external cardiac membrane ionic current and potential difference changes has been researched and analyzed.Making use of C Language,the program of the cardiac cell membrane was realized like equivalent circuit model,and the computer＇s simulation through Mat-lab software platform was realized.As a result,it obtained the result of simulation experience of electrophysiological model of cardiac muscle cell under every different kinds of stimulation.
出处
《计算机与数字工程》
2012年第4期1-2,5,共3页
Computer & Digital Engineering
