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血清sCD40L和YKL-40水平与2型糖尿病大血管并发症的关系及意义 被引量：1

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摘要 糖尿病的慢性并发症遍及全身各重要器官,包括大血管病变和微血管病变,其中大血管病主要包括心、脑血管及周围血管疾病,是引起患者致残、致死的主要原因之一,在糖尿病死亡原因中,动脉粥样硬化约占80%。新近研究发现,CD40与CD40L是一对互补跨膜糖蛋白,是新的炎症标志物,CD40L可通过与血管内皮细胞、平滑肌细胞、巨噬细胞表达的CD40相互作用,产生一系列的生物学效应。
作者 朱梅松
机构地区 浙江省桐乡市第二人民医院
出处 《上海预防医学》 CAS 2012年第4期220-222,共3页 Shanghai Journal of Preventive Medicine
关键词 2型糖尿病大血管并发症 SCD40L YKL-40 大血管病变 血清 周围血管疾病 血管内皮细胞 动脉粥样
分类号 R587.1 [医药卫生—内分泌]
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参考文献11

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二级参考文献27

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共引文献1

同被引文献36

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上海预防医学
2012年 第4期

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