脉管肿瘤与脉管畸形的临床特点及治疗

Clinical Characteristics and Therapies of Vascular Tumors and Vascular Malformations

【目的】总结脉管性疾病(脉管肿瘤与脉管畸形)住院患者的临床资料,探讨该疾病的临床特点以及治疗方式。【方法】对中山大学附属第一医院2006年1月至2009年9月期间的592例脉管肿瘤及脉管畸形住院患者的临床资料进行回顾性分析。【结果】脉管肿瘤187例(31.6%),脉管畸形405例(68.4%)。脉管肿瘤及脉管畸形最常见的受累部位分别为头颈部(41.2%)及下肢(37.0%);前者出现临床不适症状的比例(8.6%)低于后者(30.9%);前者病灶累及肌肉或骨关节的比例(12.3%)低于后者(60.1%),差异有统计学意义(P<0.001);两组在治疗方式的选择上不尽相同,差异有统计学意义(P<0.001)。【结论】脉管肿瘤与脉管畸形患者的临床特点各异,应个体化选择治疗方案。

【Objective】 This hospital based retrospective study assessed some clinical characteristics and therapies for patients with vascular anomalies（vascular tumors or vascular malformations） in southeast China.【Methods】A total of 592 vascular anomalies patients,admitted to the First Affiliated Hospital of Sun Yat-sen University from January 2006 to September 2009,were enrolled in the study.Data for clinical characteristics and therapies were collected and analyzed.【Results】 Of the 592 cases,vascular tumors and vascular malformations accounted for 31.6% and 68.4%,respectively.The most commonly involved areas of vascular tumors and vascular malformations were head and neck（41.2%） and lower limbs（37.0%）,separately.8.6% of patients with vascular tumors had definite symptoms,comparing 30.9% of patients did in vascular malformations group.12.3% of lesions involved muscle,bone or joint in vascular tumors,which was significantly lower than that（60.1%） in vascular malformations（P0.001）.What＇s more,there were different choices for therapies in these two groups.【Conclusions】 Due to the clinical heterogeneity in vascular tumors and vascular malformations,therapies should be undertaken individually.