动态测定血清甲状腺素水平在重症肺炎患者病情评价和预后预测中的价值

Evaluation and Prognostic Significance of Dynamic Serum Thyroxine Levels on the Determination of Patients with Severe Pneumonia

目的:探讨重症肺炎患者血清甲状腺素水平动态变化对病情严重程度评估、预测预后的意义。方法:对62例重症肺炎患者入住ICU后24h内、72h和第7天测定血清甲状腺素水平,并统计他们的APACHEⅡ评分,根据分值高低进行病例分组比较。同时与25例健康体检者血清甲状腺素水平对照。结果:重症肺炎病人存在SES,表现为T3、T4减低,其改变与病情的严重程度相关。死亡组患者T3、T4比存活组明显降低。结论:动态测定血清甲状腺素水平对重症肺炎患者病情评价和预后预测有一定的指导意义。

Objective： To explore dynamic change of serum thyroxine level severe pneumonia patients in serious condition, and predict the significance of the prognosis. Method： 62 cases of patients with severe pneumonia in after 24 hours, 72 hours and the seventh ICU were determined serum thyroxine level, and sta- tistics of the APACHE lI score. At the same time compared with the serum thyroxine levele of 25 cases of the healthy check-up. Result： Severe pneumonia patients had sick euthyroid syndrome （ SES ） , for the performance of the T3 , T4 level to decrease, the change and the severity of the illness of the related. Death groups of patients T3 , T4 level than live group is decreased obviously. Conclusion： Dynamic serum thyroxine levels on the determination of severe pneumonia patients after evaluation and prognostic has some significance.