摘要
目的:探讨血清胱抑素C(CysC)、尿微量清蛋白(mALB)、尿β-微球蛋白(β-MG)的变化对肝硬化患者肾功能改变的意义。方法:采用透射比浊法测定55例肝硬化患者及40例健康体检者CysC、mALB、β-MG。结果:肝硬化患者三项指标明显高于健康人,P<0.05差异有统计学意义;肝硬化CysC异常百分率明显高于健康人,比较P<0.01,差异有显著性。结论:CysC可以作为肝硬化并继发肾功能损害的首要指标,联合检测尿mALB、β-MG有利于提高早期诊断的敏感性。
Objective. To study the changes of CysC, mALB, β-MG for renal function in hepatocirrho- sis patients. Method： Using turbidimetry to determine CysC, mALB, β-MG 55 hepatocirrhosis patients and 40 healthy subjects. Result： Three index were significantly higher in patients with hepatocirrhosis than those in healthy people （ P〈0.05 }, There was statistically difference ; cirrhosis CysC percentage were significantly higher than those in healthy people （ P〈0.01） , There were significant differences. Conclusion： CysC can be used to detect hepatocirrhosis and secondary to renal damage in patients with primary index, combined determination of urinary mALB, β-MG is helpful to improve the early diagnostic sensitivity.
出处
《河北医学》
CAS
2012年第4期482-484,共3页
Hebei Medicine
关键词
胱抑素C
肝硬化
肾损害
CysC
Hepatoeirrhosis
Renal damage
