崇明地区新生儿血清及尿液中15种金属元素的含量分布探讨

Primary invastigation for the levels of 15 kinds of metal elements in serum and urine of infants from Chongming district

目的:观察崇明地区新生儿血、尿金属元素的含量分布情况,为动态研究本地区儿童体内血、尿金属元素的变化及金属元素代谢情况奠定基础。方法:采用电感耦合等离子体质谱法测定血清、尿液中15种金属元素的含量,运用K-S检验统计分析金属元素的分布情况。结果:新生儿血清中钒、铬、钴、铜和硒元素呈正态分布(P<0.05);铁和锌元素取自然对数后呈正态分布(P<0.05)。新生儿尿液中,钒、铬和铜元素呈正态分布(P<0.05);锌和钼元素取自然对数后呈正态分布(P<0.05)。结论:新生儿血清及尿液中的金属元素的含量具有地域及年龄特点,部分金属元素呈正态分布,可以作为进一步研究的基础。

Objective：To investigate the levels of 15 metal elements in serum and urine of infants from Chongming district,and provide foundation for the research of dynamic changes and metabolism about these elements in vivo.Methods：The concentrations of 15 metal elements were measured by inductively coupled plasma mass spectrometry,and the distribution of there element were analyzed by K-S tests.Results：The data of 51V,53Cr,59Co,63Cu and 82Se level in serum and urine showed normal distribution（P〈0.05）,while the data of 56Fe and 66Zn in serum,and 66Zn and 95Mo in urine showed normal distribution after natural log-transformation（P〈0.05）.Conclusions：The concentrations of metal elements in infants′serum and urine have geographic and age-related characteristics in Chongming district,which can be used as the basis for further research.