冠心病与血胰岛素水平及胰岛素敏感性的关系

The relation of blood insulin level and insulin sensitivity to coronary artery disease

目的 :探讨冠心病与血胰岛素 (INS)水平及胰岛素敏感性之间的关系。方法 :对 133例冠心病和 77例健康对照者进行血糖 (BG)、血 INS及胰岛素敏感性 (1/ BG× INS)测定。结果 :冠心病组与对照组比较 ,血糖水平无显著性差异 (P >0 .0 5 ) ,而血 INS明显增高 (P <0 .0 5 ) ,胰岛素敏感性明显下降 (P <0 .0 5 )。冠心病组内 ,单纯冠心病组及冠心病并发原发性高血压组相比较 ,两组间血糖、血 INS及胰岛素敏感性均无显著性差异 (P >0 .0 5 )。结论

Objective:To explore the relation of blood insulin level and insulin sensitivity to coronary artery disease.Method:The blood glucose (BG),blood insulin level (INS) and insulin sensitivity (1/BG×INS) were measured in 133 patients with coronary artery disease and 77 cortrol subjects.Result:There were sigficant difference (P< 0.05 ) in blood insulin level and insulin sensitivity between two groups,but no remarked difference in blood glucose level was noted.Conclusion:There were increased level of blood insulin and decreased insulin sensitivity in patients with coronary artery disease.