MoCA与MMSE对首发脑梗死患者认知功能的评估应用

Comparison of the application of Montel cognitive assessment and mini-mental state examination to cognitive function evaluation in the first-ever cerebral infarction

目的探讨蒙特利尔认知评估量表(MoCA)与简易智能状态检查量表(MMSE)在脑梗死患者认知功能评估中的应用。方法选择首发单一病灶脑梗死患者160例,在其发病3个月后,用MoCA与MMSE进行认知功能检测,并将不同性别、年龄段、受教育程度患者的MoCA与MMSE评分进行比较。结果不同性别、年龄、受教育程度患者的MoCA评分均低于MMSE评分,差异有统计学意义(P<0.01)。年龄(β=-3.176,P=0.000)、性别(β=2.189,P=0.002)、受教育程度(β=2.032,P=0.000)为MoCA评分的影响因素。结论与MMSE相比,MoCA更适用于脑梗死后认知功能障碍诊断,其评分受患者年龄、性别、受教育程度影响。

Objective To investigate the comparison of the application of Montel cognitive assessment（MoCA） and mini-mental state examination（MMSE） to cognitive function evaluation in the first-ever cerebral infarctions.Methods One hundred and sixty patients with first-ever cerebral infarction were recruited and both MoCA and MMSE were conducted to assess their cognitive functions,then the results of both scales of subjects with different genders,age and educational levels were analyzed with SPSS software.Results MoCA scores were less than MMSE scores in spite of different genders,different ages and different educational levels.The difference of the two scale scores was statistically significant.Age（β=-3.176,P=0.000）,gender（β=2.189,P=0.002）and educational level（β=2.032,P=0.000）were influential factors for MoCA scores.Conclusion MoCA is more applicable to evaluating cognitive impairment of the cerebral infarction than MMSE.The score is closely related to the age,gender and educational level of patient.