小肠原发性恶性肿瘤28例临床分析

Clinical analysis of 28 patients with primary small intestine malignant tumor

目的分析小肠原发性恶性肿瘤的临床特点。方法选取2008年1月-2011年11月在我院经病理证实的28例小肠原发性恶性肿瘤患者作为研究对象，回顾性分析其临床资料。结果小肠原发恶性肿瘤的主要临床表现有贫血、腹痛、消化道出血、腹部肿块、腹泻、发热、黄疸；发生部位以十二直肠最常见[12例（42．86％）]，空肠次之[9例（32．14％）]，回肠最少17例（25．00％）];恶性间质瘤、腺癌、恶性淋巴瘤、黑色素瘤、平滑肌肉瘤的发生率分别为42．86％（12／28）、35．71％（10／28）、14．29％（4／28）、3．57％（1／28）、3．57％（1／28）；十二指肠肿瘤的术前诊断率较高，而空回肠肿瘤术前诊断率较低。结论小肠原发恶性肿瘤由于缺乏特异的临床表现，诊断较困难，应综合多项检查，必要时行手术探查。

Objective To analyze the clinical features of primary small intestine malignant tumor. Methods Selected 28 patients with primary small intestine malignant tumor diagnosed by pathology in our hospital from January 2008 to November 2011 as study objects. Retrospectively analyzed their clinical data. Results The main clinical manifestations of primary small intestine malignant tumor were anemia, abdominal pain, gastrointestinal bleeding, abdominal mass, diarrhea, fever, and jaundice. Small intestine malignant tumors were detected in duodenum（42.86%）, jejunum（32.14%）, and ileum（25.00%）; there were 12 cases with Malignant stromal tumor（42.86%）, 10 with glandular cancer （35.71%）, 4 with malignant 1ymphoma（14.29%）, 1 with melanoma（3.57%）, and 1 with leiomyosarco,na （3.57%）.Preoperative diagnosis rate of duodenal tumor was higher than that of Jejunum ileum tumor. Conclusions Because this disease lacks specific clinical manifestation, it is difficult to make a diagnosis. Multi-examination should be applied on the diagnosis of this disease. If multi- examination fails to diagnose, doctors must consider an operation to probe.