联合用药与微创手术治疗急性重型胰腺炎的疗效对比

Analysis on clinical treatment for 60 cases of severe acute panereatitis

目的对比探讨联合用药与手术治疗急性重型胰腺炎的效果。方法抽取本院收治的60例急性重型胰腺炎患者随机分为实验组与对照组各30例，对照组行乌司他丁联合奥曲肽治疗，实验组行微创手术治疗。随访1—2个月，比较两组患者的临床指标和生化指标。结果治疗后所有患者的生化指标均优于治疗前（P〈0．05）实验组患者腹痛、腹胀、腹膜刺激征、转手术率、入ICU时间、生存率分别为（37．60±4．13）h、（44．34-8．7）h、（48．6±7．5）h、3．3％、（6．2±1．4）d、96．7％，均优于对照组（P〈0．05）。结论微创手术治疗急性重型胰腺炎可以显著提高疗效，改善患者的各项指标。

Objective To compare and study the efficacy of surgery and drug combination method in treatment for acute severe pancreatitis. Methods 60 cases of acute severe pancreatitis were randomly divided into two groups： 30 patients in control group, using ulinastatin combined with octreotide treatment 30 patients in experimental group, with minimally invasive surgery treatment. After follow-up for 1 ~ 2 months, clinical parameters and biochemical parameters of two groups were compared. Results After treatment, all patients with biochemical indicators were better than those before the treatment （P〈 0.05） between the two groups, the clinical and biochemieal indexes inexperimental group were significantly better than those in the control group （P 〈 0.05）. Conclusion Minimally invasive surgery treatment for acute severe pancreatitis can significantly improve the efficacy and patients＇ indicators.