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特发于手掌部的嗜酸性脓疱性毛囊炎1例 被引量:3

A Case of Eosinophilic Pustular Folliculitis of Palms
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摘要 患者男,19岁。左手掌反复出现水疱、脓疱伴瘙痒2月余。体检:左手掌见多处淡红色轻度脱屑性斑疹、斑片,伴有小水疱、脓疱及结痂,右手掌散在多个水疱。外周血和骨髓中嗜酸性粒细胞增多。左手掌皮损组织病理检查示:真皮及皮下组织中大量以嗜酸粒细胞为主的炎细胞浸润。诊断:嗜酸性脓疱性毛囊炎。口服强的松30mg/d后皮损迅速消退。 A 19-vear-oht man presented with pruritie vesicles and pustules for 2 inonlhs on his left pahn. Some reddish macules and patches with a few vesicles, pustules and crusts were seen on his left palm. Several vesicles were sporadically distrihuted on his right palm. Laboratory tests showed marked increase of eosinophils in the pe- ripheral blood and bone marrow. The histopathology revealed prominent inflammatory infiltration in the dermis and suhct, tis. primarily eosinophils. The case was diagnosed with eosinophilic pustular folliculitis. The patient dramatically responded to oral prednisone with the dosage of 30 mg/d.
出处 《中国皮肤性病学杂志》 CAS 北大核心 2012年第5期432-433,共2页 The Chinese Journal of Dermatovenereology
关键词 毛囊炎 嗜酸性 脓疱性 Eosinophilie Pustular Folliculitis
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参考文献5

  • 1Sufyan W,Tan KB,Wong ST. Eosinophilic pustular folliculitis[J].Archives of Pathology and Laboratory Medicine,2007,(10):1598-1601.
  • 2Aoyama H,Tagami H. Eosinophilic pustular folliculitis starting initially only with palmoplantar pustular lesions.Report of a case and review of the literature[J].Dermatology,1992,(04):276-280.
  • 3Tsuboi H,Niiyama S,Katsuoka K. Eosinophilic pustular folliculitis (Ofuji disease) manifested as pustules on the palms and soles[J].Cutis:Cutaneous Medicine for the Practitioner,2004,(02):107-110.
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同被引文献22

  • 1敖俊红,郝震锋,杨蓉娅.嗜酸性脓疱性毛囊炎[J].中国皮肤性病学杂志,2006,20(8):505-507. 被引量:6
  • 2赵辨.中国临床皮肤病学.南京:江苏科学技术出版社,2009.
  • 3Tang MB, Tan E, Chua SH. Eosinophilic pustular folliculitis ( Ofuji' s disease) in Singapore : a review of 23 adult cases. Au- stralas J Dermato1,2003,44:44-47.
  • 4Springinsfeld G, Roth B, Martinot M, et al. Immune reconstitu- tion inflammatory syndrome associated with eosinophilic pustular folliculitis in an HIV-infected patient. Med MaI Infect, 2011, 41:49-50.
  • 5Ogawa E, Okuyama R, Niizuma H, et al. eosinophilic pustular folliculitis occurring after bone marrow transplantation in a child with aplastic anaemia. Acta Derm Venereol, 2009,89 : 200-201.
  • 6Shindo M, Nakashima K, Yoshida Y, et al. Trichophyton rubrum infection histologically identical to eosinophilie pustular follieulitis. Clin Exp Dermatol, 2008,33 : 500-501.
  • 7Nervi SJ, Schwartz RA, Dmochowski M. Eosinophilie pustular folliculitis : A 40 year retrospect. J Am Acad Dermatol, 2006,55 (2) :285-289.
  • 8Nakahigashi K, Doi H, Otsuka A, et al. PGD2 induces eotaxin -3 via PPARgamma from sebocytes: a possible pathogenesis ofeosinophilic pustular folliculitis. J Allergy Clin Immunol, 2012, 129 : 536-543.
  • 9Murayama T, Nakamura K, Tsuchida T. Eosinophilic pustular folliculitis with extensive distribution : correlation of serum TARC levels and peripheral blood eosinophil numbers. Int J Dermatol, 2014[ Epub ahead print].
  • 10Lambert J, Berneman Z, Dockx P, et al. Eosinophilic pustular folliculitis and B-cell chronic lymphatic leukaemia. Dermatolo- gy, 1994,189( Suppl 2) :58-59.

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