MSCT通过肺叶比例异常预测COPD早期病变

The clinical value of MSCT with deep inspiration and expiratory phase in COPD

目的探讨多层螺旋CT(MSCT)对慢性阻塞性肺病(COPD)早期病变的预测。方法选择30例临床诊断为COPD的患者为病例组,对照组为34例CT胸部体检且肺功能正常者,比较深吸气相与深呼气相病例组与对照组MSCT各容积及百分比的差异。结果病例组与对照组MSCT容积指标比较,左肺、右肺、左肺上叶、左肺下叶、右肺上叶、右肺中叶、右肺下叶在吸气相(t=-8.9547、-8.449、-5.697、-7.926、-5.736、-8.059、-7.399),呼气相(t=-10.6769、-10.041、-10.407、-8.512、-9.263、-9.213、-7.479),差异均有统计学意义;2组百分比指标比较,吸气相右肺中叶(t=-2.924,P=0.005)、左肺上叶(t=3.393,P=0.001)及呼气相右肺上叶(t=-2.638,P=0.011),差异亦均有统计学意义。结论 MSCT测量肺叶容积百分比的异常能够提示COPD早期病变。

Objective To predict the pristine pathological change in COPD by MSCT.Methods 30 patients diagnosed with COPD by clinician（case of a particular disease group）,and 34 people were normal who were checked-up by PFT and chest MSCT（control group）.The differences of every lobe of lung volume and a part of percentage were compared between disease group and control group in final deep inhale end and final deep exhale end.Results Lung volume of each lobe and a part of percentage between disease group and control group in final deep inhale end and final deep exhale end had the statistical significance（P0.05）.Conclusion Lobe of lung percentage could express the pristine pathological change in COPD.