住院患者双重及多重耐药菌感染的调查

Investigation on infection of double and multiple drug resistant bacteria

目的调查研究住院患者双重及多种耐药菌感染的状况及控制措施。方法收集2011年8～10月间入住我院的389例感染性疾病患者的临床资料,并进行回顾性分析。结果 389患者中共有47例患者诊断为双重及多重耐药菌感染,其中31例患者为社区获得性感染,16例为医院获得性感染,所占比例分别为65.96%、34.04%,两组之间比较差异有统计学意义(P<0.05)。双重及多重耐药菌感染的病人数占住院患者总感染人数的12.08%,其中以神经外科、神经内科、儿科、呼吸内科及重症监护室等科室中感染率较高,共25例,占全部双重及多重耐药菌感染的53.19%。结论医院获得性感染是双重及多重耐药菌感染的主要途径,通过合理应用抗生素可以有效控制并降低双重及多重耐药菌感染对患者产生的不良影响。

Objective To investigate the status and control measures of double and multiple drug-resistant bacteria infection.Methods The clinical data of 389 patients with infectious diseases,admitted in our hospital from August 2011 to October 2011,was analyzed retrospectively.Results Among the 389 patients,47 were diagnosed as double and multiple drug-resistant infections,of which 31 (65.96%) were with community-acquired infection,16 (34.04%) were with hospital-acquired infections.Statistically significant difference was found between the two groups (P<0.05).Patients with double and multiple drug-resistant infections accounted for 12.08% of the patients with infections.53.19% of the patients with double and multiple drug-resistant infections (a total of 25 cases) distribute in the Department of neurosurgery,neurology,pediatrics,respiratory medicine and intensive care unit and other departments.Conclusion Hospital-acquired infection is the major pathway of double and multiple drug-resistant infections,which can be controlled through rational use of antibiotics.