肝硬化并发自发性细菌性腹膜炎预后的相关因素分析

A retrospective analysis of the correlation factors influencing the prognosis of liver cirrhosis combined with spontaneous bacterial peritonitis

目的分析肝硬化并发自发性细菌性腹膜炎(SBP)患者的临床特点和实验室检查数据,为临床判定其预后提供依据。方法回顾性分析68例肝硬化并发SBP患者的临床资料,根据其预后分为存活组(47例)和死亡组(21例),比较两组病例Child-Pugh评分、腹水中性粒细胞(PMN)数目、重要生化指标、并发症的因素。结果 SBP患者有较高死亡率,死亡组Child-Pugh评分、腹水中性粒细胞(PMN)数目、血肌酐值(Scr)明显高于存活组;腹水白蛋白值、血钠水平明显低于存活组,合并并发症多于存活组。结论 Child-Pugh评分、腹水中性粒细胞(PMN)数目、腹水白蛋白值、低血钠水平、血Scr值及合并并发症等因素均影响肝硬化并发SBP患者转归,临床医师可根据以上检查结果评估患者的预后。

Objective To analyze the clinical characteristics and laboratory data of liver cirrhosis patients complicated with spontaneous bacterial peritonitis（SBP）,which provide proof for exploring the factors influencing the prognosis of this disease.Methods Clinical data of 68 patients with liver cirrhosis combined with SBP were analyzed retrospectively.Cases were divided into alive group（n=47） and dead group（n=21） according to their prognosis.Child-Pugh score,the Polymorphonuclear（PMN） cells in ascites,important biochemical indicates and complications of the two groups were compared.Results SBP patients had a higher mortality rate.Child-Pugh score,the PMN cells in ascites and Scr value in dead group were significantly enhanced compared with those of alive group.Ascites albumin value and serum sodium level in dead group were significantly lower than those of alive group.But complications in dead group were significantly higher than those of alive group.Conclusion Child-Pugh score,the PMN cells in ascites,ascites albumin value,low serum sodium level,Scr value and complications can influence the survival rate of liver cirrhosis combined with SBP,through which clinical physicians can estimate the prognosis.